Quinolines and derivatives
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Filtered Search Results
Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000743885 RESIQUIMOD 50MG
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Ambeed AMBEED
5000868881 4-BROMOQUINOLINE-2-CARBOXY 1GR
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000378171 STF-083010 200MG
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TARGETMOL CHEMICALS INC Amcinonide 200MG
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Also available in 1 mL, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Amcinonide (CL-34699) is a Corticosteroid. The mechanism of action of amcinonide is as a Corticosteroid Hormone Receptor Agonist. Purity 99.9%
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eMolecules 5622-36-6 | METHYL 2-(QUINOLIN-6-YL)ACETATE | AstaTech | MFCD04038669 | 201.225 | C12H11NO2 | 95.000 | COC(=O)Cc1ccc2ncccc2c1 | 5g | 392628209
METHYL 2-(QUINOLIN-6-YL)ACETATE | AstaTech | 5622-36-6 | MFCD04038669 | 201.225 | C12H11NO2 | 95.000 | COC(=O)Cc1ccc2ncccc2c1 | 5g | 392628209
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Apexbio Technology LLC Cy5.5 alkyne (non-sulfonated) 25mg
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Cy5 5 alkyne non-sulfonated is a near-infrared fluorescent cyanine derivative equipped with an alkyne functional group for click chemistry applications Through copper-catalyzed azide-alkyne cycloaddition (CuAAC) it forms covalent conjugates with azide-containing biomolecules metabolites or small-molecule ligands Cy5 5 alkyne non-sulfonated is primarily soluble in organic solvents aqueous solutions containing organic co-solvent such as DMSO may be used during conjugation Based on these chemical properties Cy5 5 alkyne non-sulfonated holds research potential in labeling nucleic acids peptides proteins lipids and other biomolecules for biomedical imaging tissue distribution evaluation and related pharmaceutical research applications
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TARGETMOL CHEMICALS INC DMOG 200MG
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Also available in 1 mL, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. DMOG (Dimethyloxalylglycine), an antagonist of the alpha-ketoglutarate cofactor, is an inhibitor for HIF prolyl hydroxylase. Purity 98.26%
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TARGETMOL CHEMICALS INC SPP-86 10MG
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Also available in 1 mL, 1 mg, 5 mg, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. SPP-86 is an effective and selective cell-permeable inhibitor of RET tyrosine kinase with an IC50 of 8 nM. Purity 98.19%
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Apexbio Technology LLC Proflavine Hemisulfate 1811-28-5 50mg
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Proflavine Hemisulfate (CAS 1811-28-5) is a small-molecule inhibitor targeting DNA It is designed to intercalate into DNA strands thereby disrupting DNA replication and transcription Proflavine Hemisulfate exerts its biological activity primarily through DNA intercalation In in vitro studies Proflavine Hemisulfate demonstrates antimicrobial activity with reported IC50 values for inhibiting bacterial growth typically ranging between 1 10 M depending on the microbial strain and assay conditions used Based on these pharmacological properties Proflavine Hemisulfate holds research potential in studies of antimicrobial activity DNA replication assays mutagenesis and evaluating sensitivity and resistance profiles of microorganisms
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TARGETMOL CHEMICALS INC NGD 94-1 5MG
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Also available in 1 mg, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. NGD 94-1 is a selective D4 receptor antagonist with an affinity of 3 nM for the D4 receptor and greater than 2 pM for the D1, D2, D3, and D5 receptors.NGD 94-1 can be used in the study of cognitive disorders and other psychiatric disorders. Purity 99.84%
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Apexbio Technology LLC HA14-1 65673-63-4 200mg
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HA14-1 (CAS 65673-63-4) is a small molecule inhibitor of B-cell lymphoma 2 (Bcl-2) protein By binding to the BH3 domain of Bcl-2 HA14-1 antagonizes its anti-apoptotic function thereby promoting the activation of pro-apoptotic proteins such as Bax In NIH3T3 HL60 and H1299 cell lines HA14-1 induces apoptosis with reported IC50 values ranging from 10 to 20 M Additionally it has been shown to inhibit ceramide glucosyltransferase HA14-1 is widely utilized as a chemical tool to investigate Bcl-2-mediated apoptotic pathways and is of interest in cancer research exploring targeted induction of cell death
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Apexbio Technology LLC Epalrestat 82159-09-9 200mg
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Epalrestat (CAS 82159-09-9) is an orally available inhibitor of aldose reductase the rate-limiting enzyme of the polyol pathway involved in glucose metabolism By suppressing aldose reductase activity epalrestat limits intracellular sorbitol accumulation in neural tissues a process implicated in diabetic complications This compound is frequently employed in experimental models of diabetic neuropathy to investigate how modulation of the polyol pathway affects disease pathology and cellular signaling Epalrestat thus serves as a valuable molecular tool for elucidating the pathophysiology and pharmacology relevant to diabetes-associated neuronal damage
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Apexbio Technology LLC Quinidine 56-54-2 250mg
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Quinidine (CAS 56-54-2) is a small-molecule inhibitor targeting sodium (Na ) and potassium (K ) ion channels It is designed to inhibit these ion channel currents thereby modulating cardiac electrophysiological processes Quinidine exerts its biological activity primarily through inhibition of Na and K currents In in vitro studies quinidine demonstrates inhibitory activity with an IC50 of approximately 41 M on the transient outward potassium current (Ik) at a membrane potential of 0 mV Based on these pharmacological properties quinidine holds research potential in the fields of cardiac electrophysiology ion channel pharmacology drug metabolism and drug-drug interaction mechanisms
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Apexbio Technology LLC Tebuconazole 107534-96-3 200mg
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Tebuconazole (CAS 107534-96-3) is a small-molecule inhibitor targeting CYP51 a key enzyme in fungal sterol biosynthesis It modulates CYP51 activity to regulate sterol production within fungal cells Tebuconazole exerts its biological activity primarily through inhibition of CYP51 In cell-based assays tebuconazole demonstrates inhibitory activity with an IC50 value of 0 9 M against CaCYP51 from Candida albicans and 1 3 M against truncated human 60HsCYP51 Additionally in HepG2 cells tebuconazole induces lipid accumulation and oxidative stress and in mammary epithelial MAC-T cells it reduces proliferation and induces endoplasmic reticulum stress-mediated apoptosis Based on these pharmacological properties tebuconazole holds research potential in studies of fungal sterol biosynthesis cellular stress response pathways and apoptosis mechanisms
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TARGETMOL CHEMICALS INC Levosimendan 200MG
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Also available in 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. Levosimendan (OR1259) is a calcium sensitizer used in the management of acutely decompensated congestive heart failure. It increases the sensitivity of the heart to calcium, thus increasing cardiac contractility without a rise in intracellular calcium. Levosimendan exerts its effect by increasing calcium sensitivity of myocytes by binding to cardiac troponin C in a calcium-dependent manner. Purity 99.7%
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